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KLK7 |
Also Known As: protease serine 6, kallikrein 7, PRSS6,
SCCE, and
stratum corneum chymotryptic enzyme
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein. Predicted molecular weight of 27.6kDa. [provided by RefSeq]
Antibodies to KLK7:
5A5
6C12 |
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