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KLK8 |
Also Known As:
kallikrein 8, TADG-14,
NP,
HNP, HRNP,
protease serine 19,
neuropsin type 1 and type 2,
KLK8 protein type 1 and type 2, ovasin, and PRSS19
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KLK8 (TADG-14) Kallikreins are a
subgroup of serine proteases having diverse physiological functions. Growing evidence
suggests that many kallikreins are implicated in carcinogenesis and some have potential
as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein
subfamily members located in a cluster on chromosome 19. Alternate splicing of this
gene results in four transcript variants encoding four different isoforms. The isoforms
exhibit distinct patterns of expression that suggest roles in brain plasticity and
ovarian cancer. Predicted molecular weight of largest isoform is 33kDa. [provided
by RefSeq]
Antibodies to KLK8:
AJE
4C7B12 |
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